Familjen Spengler återvänder till platsen där allt började - den ikoniska brandstationen i New York. De slår sig samman med det ursprungliga Ghostbustersgänget, som har skapat ett topphemligt forskningslabb som tar infångandet av spöken till nästa nivå. När upptäckten av en gammal artefakt frigör en ond kraft, måste de gamla och de nya spökjägarna samarbeta för att skydda sitt hem och rädda världen från en andra istid.
The Vanderhouvens are a typical family...except a curse recently turned Alex—their loving husband and father—to stone. In order to save him, his wife and kids set out on spine-tingling adventures to return ancient artifacts stolen by an ancestor.
In the bustling and noisy modern city, time silently accumulates. Those rare treasures from myths and legends, once lost in the river of time, are now here — in an antique shop called "YaShe". The shop owner, Gan Bizhi, possesses the ability to listen to ancient artifacts, helping them find their destined owners and fulfill their long-held wishes. He befriends a warm-hearted doctor, Su Beilu, and they become close friends. Only the owner knows that the doctor also harbors something extraordinary...
Ex-con Cal McTeer's return to her hometown of Orphelin Bay blows the lid off a generations-long conspiracy of silence around murder, drugs and Sirens.
